Journal of Basic and Clinical Reproductive Sciences

Journal of Basic and Clinical Reproductive Sciences
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Nahla Kazim

Tawam Fertility Centre, UAE


  • Short communication
    Spontaneous OHSS in successful pregnancy following artificial FET cycle: A case report
    Author(s): Nahla Kazim

    Ovarian hyperstimulation syndrome is a disorder associated with exogenous gonadotropin and is an iatrogenic complication of ovulation induction therapy in ART during the luteal phase and or early stages of pregnancy. Severe OHSS is considered a life-threatening condition and occurs in 0.2-1.2% of stimulated cycles. In literature, sporadic cases of spontaneous OHSS have been reported amongst naturallyconceived pregnancies and non-pregnant women with primary hypothyroidism, polycystic ovarian disease, molar pregnancies, pituitary adenomas and in women with Follicle Stimulating Hormone (FSH) receptor mutations. The characteristic pathophysiology of OHSS is due to release of number of vasoactive amines including Vascular Endothelial Growth Factor (VEGF) and other pro-inflammatory factors resulting in increased capillary permeability, leakage of fluid from the vasculature, third space flui.. Read More»

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Citations : 14972

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