Journal of Basic and Clinical Reproductive Sciences

Journal of Basic and Clinical Reproductive Sciences
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

The role of Ca+2 oscillator in oocytes activation with different types of sperms

Author(s): Aya Al-Ibraheemi, Noureddine Louanjli, Mohamed Zarqaoui, Mohamed Ennaji, Wassym R. Senhaji, Mustafa Zakaria, Ritu S. Santwani and Romaissa Boutiche

This research article has been made to demonstrate the oocytes activation process and how it's related to Ca2+ oscillation. Moreover, the research shows how Ca2+ oscillation is transition pattern can be affected by the sperm types. It has been found that the oocysts activation depends on intercellular factors and single transduction which is mainly activated by Ca2+ oscillation. Ca2+ oscillation induction can have a different pattern in different spices, but it depends chiefly on one factor which the sperm-oocytes fusion. Through fertilization, the spermatozoon produces a series of low- long-lasting Ca2+ oscillations frequency. It is usually believed that these oscillations are caused by to Ca2+ release into the Inositol 1,4,5-Trisphosphate (InsP3) receptor. Thus, the Ca2+ oscillation can also relay on the type of sperm injected to the oocytes where it has been found that round spermatid is not as effective as spermatozoon to induce Ca2+ oscillation. Although round spermatid can be used in cases such as severe azoospermia, where no spermatozoon is available, with the help of artificial oocytes activation.


Annals of Medical and Health Sciences Research Journal of Basic and Clinical Reproductive Sciences is a peer-reviewed online journal with Semiannual print on demand compilation of issues published.
+44-151-808-0171
Submit your Manuscript

  • Flexible online submission
  • Preliminary quality report within 3 days
  • 21 days rapid peer-review
  • High visibility of published content
  • Associated with relevant global conferences
  • 24/7 Editorial office availability